Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

21 papers

NM_006182.4

p.I638F

c.1912A>T

Surrounding Variants

1 paper

NM_006182.4

p.I638I

c.1914C>T

1 paper

NM_006182.4

p.I637N

c.1910T>A

1 paper

NM_006182.4

p.L640P

c.1919T>C

2 papers

NM_006182.4

p.P635Q

c.1904C>A

1 paper

NM_006182.4

p.P635fs

c.1903_1904fs

1 paper

NM_006182.4

p.L641S

c.1922T>C

1 paper

NM_006182.4

p.P635delFs

c.1904delC

1 paper

NM_006182.4

p.D634Y

c.1900G>T

1 paper

NM_006182.4

p.K633N

c.1899G>C

1 paper

NM_006182.4

p.K633N

c.1899G>T

1 paper

NM_006182.4

p.V643L

c.1927G>C

1 paper

NM_006182.4

p.V643L

c.1927G>T