Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006182.4

p.M657I

c.1971G>A

Surrounding Variants

2 papers

NM_006182.4

p.M657I

c.1971G>C

2 papers

NM_006182.4

p.M657I

c.1971G>T

1 paper

NM_006182.4

p.E658K

c.1972G>A

1 paper

NM_006182.4

p.E658*

c.1972G>T

1 paper

NM_006182.4

p.E658D

c.1974G>C

1 paper

NM_006182.4

p.E658D

c.1974G>T

1 paper

NM_006182.4

p.Y656C

c.1967A>G

1 paper

NM_006182.4

p.G660*

c.1978G>T

3 papers

NM_006182.4

p.E655K

c.1963G>A

1 paper

NM_006182.4

p.G660V

c.1979G>T

1 paper

NM_006182.4

p.G660_D661insFs

c.1980_1981insG

2 papers

NM_006182.4

p.T654N

c.1961C>A