Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.F665Y

c.1994T>A

Surrounding Variants

1 paper

NM_006182.4

p.L666I

c.1996C>A

1 paper

NM_006182.4

p.N663H

c.1987A>C

2 papers

NM_006182.4

p.S667S

c.2001C>A

1 paper

NM_006182.4

p.R668S

c.2002C>A

7 papers

NM_006182.4

p.R668C

c.2002C>T

7 papers

NM_006182.4

p.R668H

c.2003G>A

1 paper

NM_006182.4

p.H669R

c.2006A>G

1 paper

NM_006182.4

p.H669Q

c.2007C>A

1 paper

NM_006182.4

p.H669Q

c.2007C>G

1 paper

NM_006182.4

p.D661N

c.1981G>A

1 paper

NM_006182.4

p.D661Y

c.1981G>T

1 paper

NM_006182.4

p.G660_D661insFs

c.1980_1981insG