Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.V682I

c.2044G>A

Surrounding Variants

1 paper

NM_006182.4

p.T681N

c.2042C>A

8 papers

NM_006182.4

p.T681I

c.2042C>T

1 paper

NM_006182.4

p.S683I

c.2048G>T

2 papers

NM_006182.4

p.R680H

c.2039G>A

1 paper

NM_006182.4

p.R680L

c.2039G>T

1 paper

NM_006182.4

p.R680G

c.2038C>G

2 papers

NM_006182.4

p.R680C

c.2038C>T

1 paper

NM_006182.4

p.D678N

c.2032G>A

1 paper

NM_006182.4

p.D678Y

c.2032G>T

1 paper

NM_006182.4

p.S677R

c.2031C>G

1 paper

NM_006182.4

p.S677delins

c.2029_2030delinsTT

1 paper

NM_006182.4

p.S676S

c.2028C>A