Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006182.4

p.R714Q

c.2141G>A

Surrounding Variants

6 papers

NM_006182.4

p.R714*

c.2140C>T

9 papers

NM_006182.4

p.T713I

c.2138C>T

1 paper

NM_006182.4

p.C716Y

c.2147G>A

1 paper

NM_006182.4

p.V718M

c.2152G>A

1 paper

NM_006182.4

p.D710H

c.2128G>C

1 paper

NM_006182.4

p.D710Y

c.2128G>T

3 papers

NM_006182.4

p.G719S

c.2155G>A

5 papers

NM_006182.4

p.G719C

c.2155G>T

1 paper

NM_006182.4

p.R709Q

c.2126G>A

5 papers

NM_006182.4

p.G719A

c.2156G>C

5 papers

NM_006182.4

p.R709*

c.2125C>T

1 paper

NM_006182.4

p.H708Q

c.2124C>A