Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.T765T

c.2295T>G

Surrounding Variants

7 papers

NM_006182.4

p.T765P

c.2293A>C

1 paper

NM_006182.4

p.F764S

c.2291T>C

1 paper

NM_006182.4

p.A767G

c.2300C>G

1 paper

NM_006182.4

p.F764V

c.2290T>G

25 papers

NM_006182.4

p.S768R

c.2302A>C

1 paper

NM_006182.4

p.K763T

c.2288A>C

2 papers

NM_006182.4

p.K763E

c.2287A>G

1 paper

NM_006182.4

p.S768N

c.2303G>A

12 papers

NM_006182.4

p.S768I

c.2303G>T

26 papers

NM_006182.4

p.S768R

c.2304T>A

25 papers

NM_006182.4

p.S768R

c.2304T>G

1 paper

NM_006182.4

p.D769H

c.2305G>C