Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.V770L

c.2308G>C

Surrounding Variants

1 paper

NM_006182.4

p.V770L

c.2308G>T

1 paper

NM_006182.4

p.V770E

c.2309T>A

1 paper

NM_006182.4

p.D769_V770ins3

c.2307_2308ins9

1 paper

NM_006182.4

p.V770_W771ins1

c.2310_2311insGGT

1 paper

NM_006182.4

p.D769H

c.2305G>C

1 paper

NM_006182.4

p.D769Y

c.2305G>T

1 paper

NM_006182.4

p.W771ins3

c.2311_2312ins9

2 papers

NM_006182.4

p.W771*

c.2312G>A

26 papers

NM_006182.4

p.S768R

c.2304T>A

25 papers

NM_006182.4

p.S768R

c.2304T>G

2 papers

NM_006182.4

p.W771*

c.2313G>A

1 paper

NM_006182.4

p.S768N

c.2303G>A