Varaico: Literature-Extracted Genetic Variants

DDR2

688 papers

RefSeq Summary

This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironme...

Pfam Domains

F5_F8_type_Caa 45–182UCSCF5/8 type C domain

DDR1-2_DS-likeaa 190–366UCSCDiscoidin domain-containing receptor 1/2, DS-like domain

PK_Tyr_Ser-Thraa 563–849UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

discoidin domain receptor tyrosine kinase 2

HGNC Previous Symbols

TYRO10; NTRKR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006182.4

p.F805V

c.2413T>G

Surrounding Variants

1 paper

NM_006182.4

p.F805S

c.2414T>C

1 paper

NM_006182.4

p.R806R

c.2416C>A

1 paper

NM_006182.4

p.R806*

c.2416C>T

1 paper

NM_006182.4

p.F804I

c.2410T>A

3 papers

NM_006182.4

p.R806Q

c.2417G>A

1 paper

NM_006182.4

p.Q808K

c.2422C>A

2 papers

NM_006182.4

p.Q808*

c.2422C>T

1 paper

NM_006182.4

p.Q808H

c.2424A>C

1 paper

NM_006182.4

p.Q808H

c.2424A>T

1 paper

NM_006182.4

p.G809R

c.2425G>A

1 paper

NM_006182.4

p.G809R

c.2425G>C

1 paper

NM_006182.4

p.G809W

c.2425G>T