Varaico: Literature-Extracted Genetic Variants

DDX10

120 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ...

Pfam Domains

DEADaa 93–263UCSCDEAD/DEAH box helicase

Helicase_Caa 299–410UCSCHelicase conserved C-terminal domain

CTE_SPB4aa 461–510UCSCATP-dependent rRNA helicase SPB4-like, C-terminal extension

Gene Aliases

HGNC Name

DEAD-box helicase 10

HGNC Alias Symbols

HRH-J8; Dbp4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004398.4

p.E394K

c.1180G>A

Surrounding Variants

2 papers

NM_004398.4

p.V384M

c.1150G>A

1 paper

NM_004398.4

p.D380E

c.1140T>A

1 paper

NM_004398.4

p.R408G

c.1222A>G

1 paper

NM_004398.4

p.D380E

c.1140T>A

1 paper

NM_004398.4

p.D380E

c.1140T>G

1 paper

NM_004398.4

p.A366T

c.1096G>A

2 papers

NM_004398.4

p.R363H

c.1088G>A

1 paper

NM_004398.4

p.R363S

c.1087C>A

1 paper

NM_004398.4

p.R363C

c.1087C>T

1 paper

NM_004398.4

p.Y358F

c.1073A>T

1 paper

NM_004398.4

p.Q350*

c.1048C>T

1 paper

NM_004398.4

p.P338R

c.1013C>G