Varaico: Literature-Extracted Genetic Variants

DDX10

120 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ...

Pfam Domains

DEADaa 93–263UCSCDEAD/DEAH box helicase

Helicase_Caa 299–410UCSCHelicase conserved C-terminal domain

CTE_SPB4aa 461–510UCSCATP-dependent rRNA helicase SPB4-like, C-terminal extension

Gene Aliases

HGNC Name

DEAD-box helicase 10

HGNC Alias Symbols

HRH-J8; Dbp4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004398.4

p.R408Splc

c.1224-64C>G

Surrounding Variants

2 papers

NM_004398.4

p.K410E

c.1228A>G

1 paper

NM_004398.4

p.D412E

c.1236T>A

1 paper

NM_004398.4

p.D412E

c.1236T>G

4 papers

NM_004398.4

p.V427L

c.1279G>C

4 papers

NM_004398.4

p.V427L

c.1279G>T

1 paper

NM_004398.4

p.P436L

c.1307C>T

1 paper

NM_004398.4

p.E445G

c.1334A>G

1 paper

NM_004398.4

p.Q460*

c.1378C>T

1 paper

NM_004398.4

p.Q462R

c.1385A>G

1 paper

NM_004398.4

p.D463Y

c.1387G>T

1 paper

NM_004398.4

p.R470_C471Splc

c.1410+1G>A