defensin beta 105B

defensin, beta 105B

Beta-defensin 105

Beta-defensin 5

Defensin, beta 105

BD-5

DEFB-5

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105B, represents the more telomeric copy. [provided by RefSeq, Oct 2014].

Varaico: Literature-Extracted Genetic Variants

DEFB105B

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name