defensin beta 107A

DEFB107

DEFB-7

defensin, beta 107A

Beta-defensin 107

Beta-defensin 7

Defensin, beta 107

BD-7

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Oct 2014].

Varaico: Literature-Extracted Genetic Variants

DEFB107A

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol