Varaico: Literature-Extracted Genetic Variants

DGKZ

71 papers

RefSeq Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling casca...

Pfam Domains

C1_1aa 172–231UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

DAGK_cataa 295–416UCSCDiacylglycerol kinase catalytic domain

DAGK_accaa 446–603UCSCDiacylglycerol kinase accessory domain

DGKIaa 642–751UCSCDiacylglycerol kinase iota-like domain

Ankaa 822–853UCSCAnkyrin repeat

Ankaa 857–889UCSCAnkyrin repeat

Gene Aliases

HGNC Name

diacylglycerol kinase zeta

HGNC Alias Symbols

DAGK5; hDGKzeta; DGK-ZETA; DAGK6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001199267.2

p.K211*

c.631A>T

Surrounding Variants

1 paper

NM_001199267.2

p.V218M

c.652G>A

1 paper

NM_001199267.2

p.Q225Q

c.675G>A

1 paper

NM_001199267.2

p.E227Q

c.679G>C

1 paper

NM_001199267.2

p.K260R

c.779A>G

1 paper

NM_001199267.2

p.G352E

c.1055G>A

1 paper

NM_001199267.2

p.G355D

c.1064G>A

1 paper

NM_001199267.2

p.H186N

c.556C>A

1 paper

NM_001199267.2

p.G182S

c.544G>A

1 paper

NM_001199267.2

p.R179H

c.536G>A

1 paper

NM_001199267.2

p.R178Q

c.533G>A

1 paper

NM_001199267.2

p.S362_P373del12

c.1084_1118del36

1 paper

NM_001199267.2

p.G395C

c.1183G>T