Varaico: Literature-Extracted Genetic Variants

DGKZ

71 papers

RefSeq Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling casca...

Pfam Domains

C1_1aa 172–231UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

DAGK_cataa 295–416UCSCDiacylglycerol kinase catalytic domain

DAGK_accaa 446–603UCSCDiacylglycerol kinase accessory domain

DGKIaa 642–751UCSCDiacylglycerol kinase iota-like domain

Ankaa 822–853UCSCAnkyrin repeat

Ankaa 857–889UCSCAnkyrin repeat

Gene Aliases

HGNC Name

diacylglycerol kinase zeta

HGNC Alias Symbols

DAGK5; hDGKzeta; DGK-ZETA; DAGK6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001199267.2

p.R628Q

c.1883G>A

Surrounding Variants

2 papers

NM_001199267.2

p.A631T

c.1891G>A

3 papers

NM_001199267.2

p.A608T

c.1822G>A

3 papers

NM_001199267.2

p.L581L

c.1741C>T

1 paper

NM_001199267.2

p.E579K

c.1735G>A

1 paper

NM_001199267.2

p.H577Y

c.1729C>T

1 paper

NM_001199267.2

p.A571T

c.1711G>A

1 paper

NM_001199267.2

p.Q647K

c.1939C>A

1 paper

NM_001199267.2

p.S652T

c.1955G>C

1 paper

NM_001199267.2

p.G541V

c.1622G>T

1 paper

NM_001199267.2

p.S712F

c.2135C>T

1 paper

NM_001199267.2

p.F717S

c.2150T>C

1 paper

NM_001199267.2

p.V526I

c.1576G>A