Varaico: Literature-Extracted Genetic Variants

Gene:DHFR
Variant:p.F35S

DHFR

423 papers

RefSeq Summary

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the function...

Pfam Domains

DHFR_1aa 4–126UCSCDihydrofolate reductase

Gene Aliases

HGNC Name

dihydrofolate reductase

HGNC Alias Symbol

DHFR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000791.4
p.F35S
c.104T>C
Surrounding Variants
1 paper
NM_000791.4
p.F35L
c.105C>A
2 papers
NM_000791.4
p.Q36E
c.106C>G
1 paper
NM_000791.4
p.R37K
c.110G>A
1 paper
NM_000791.4
p.F32delFs
c.95delA
2 papers
NM_000791.4
p.M38K
c.113T>A
1 paper
NM_000791.4
p.F32fs
c.94_95fs
1 paper
NM_000791.4
p.T39S
c.115A>T
1 paper
NM_000791.4
p.T39A
c.115A>G
1 paper
NM_000791.4
p.T39I
c.116C>T
1 paper
NM_000791.4
p.T39S
c.116C>G
1 paper
NM_000791.4
p.T39T
c.117C>A
1 paper
NM_000791.4
p.T40I
c.119C>T
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