Varaico: Literature-Extracted Genetic Variants

Gene:DHFR
Variant:p.M15K

DHFR

423 papers

RefSeq Summary

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the function...

Pfam Domains

DHFR_1aa 4–126UCSCDihydrofolate reductase

Gene Aliases

HGNC Name

dihydrofolate reductase

HGNC Alias Symbol

DHFR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000791.4
p.M15K
c.44T>A
Surrounding Variants
1 paper
NM_000791.4
p.Q13H
c.39G>C
1 paper
NM_000791.4
p.I17fs
c.49_50fs
1 paper
NM_000791.4
p.G18C
c.52G>T
1 paper
NM_000791.4
p.G18V
c.53G>T
5 papers
NM_000791.4
p.S12F
c.35C>T
1 paper
NM_000791.4
p.S12Y
c.35C>A
1 paper
NM_000791.4
p.G18G
c.54C>T
1 paper
NM_000791.4
p.G18fs
c.52_53fs
1 paper
NM_000791.4
p.K19*
c.55A>T
2 papers
NM_000791.4
p.V11A
c.32T>C
1 paper
NM_000791.4
p.A10insFs
c.29_30insC
2 papers
NM_000791.4
p.G18_K19del0
c.52_57del6
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."