Varaico: Literature-Extracted Genetic Variants

DHX35

54 papers

RefSeq Summary

DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary s...

Pfam Domains

Helicase_Caa 260–398UCSCHelicase conserved C-terminal domain

WHD_HA2aa 459–488UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 489–548UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 606–685UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

Gene Aliases

HGNC Name

DEAH-box helicase 35

HGNC Previous Symbols

C20orf15; DDX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021931.4

p.Q284_E285Splc

c.853-3T>A

Surrounding Variants

1 paper

NM_021931.4

p.V290A

c.869T>C

1 paper

NM_021931.4

p.F280L

c.840T>A

1 paper

NM_021931.4

p.F280L

c.840T>G

1 paper

NM_021931.4

p.F280L

c.838T>C

1 paper

NM_021931.4

p.D274D

c.822C>T

1 paper

NM_021931.4

p.V254D

c.761T>A

1 paper

NM_021931.4

p.P253L

c.758C>T

1 paper

NM_021931.4

p.Q251E

c.751C>G

1 paper

NM_021931.4

p.V245fs

c.733_734fs

1 paper

NM_021931.4

p.T237T

c.711A>G

1 paper

NM_021931.4

p.T237A

c.709A>G

1 paper

NM_021931.4

p.T225T

c.675C>T