Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

1–12 of 180 variants

21 papers

NM_032656.4

p.R308Q

c.923G>A

11 papers

NM_032656.4

p.L467V

c.1399C>G

10 papers

NM_032656.4

p.R487H

c.1460G>A

9 papers

NM_032656.4

p.R334W

c.1000C>T

8 papers

NM_032656.4

p.T477M

c.1430C>T

8 papers

NM_032656.4

p.R674W

c.2020C>T

7 papers

NM_032656.4

p.E168del1

c.502_503delCTC

7 papers

NM_032656.4

p.R390H

c.1169G>A

7 papers

NM_032656.4

p.A492P

c.1474G>C

7 papers

NM_032656.4

p.R674Q

c.2021G>A

7 papers

NM_032656.4

p.A737T

c.2209G>A

7 papers

NM_032656.4

p.G1030E

c.3089G>A