Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_032656.4

p.G1030E

c.3089G>A

Surrounding Variants

1 paper

NM_032656.4

p.E1028K

c.3082G>A

6 papers

NM_032656.4

p.V999M

c.2995G>A

2 papers

NM_032656.4

p.V996I

c.2986G>A

1 paper

NM_032656.4

p.P1048H

c.3143C>A

2 papers

NM_032656.4

p.A1049T

c.3145G>A

1 paper

NM_032656.4

p.A1065A

c.3195C>T

1 paper

NM_032656.4

p.E978K

c.2932G>A

1 paper

NM_032656.4

p.P977S

c.2929C>T

1 paper

NM_032656.4

p.V1073delFs

c.3217delC

1 paper

NM_032656.4

p.K1076T

c.3227A>C

5 papers

NM_032656.4

p.R1081Q

c.3242G>A

4 papers

NM_032656.4

p.T1094M

c.3281C>T