Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_032656.4

p.R674W

c.2020C>T

Surrounding Variants

7 papers

NM_032656.4

p.R674Q

c.2021G>A

1 paper

NM_032656.4

p.T675M

c.2024C>T

1 paper

NM_032656.4

p.T675T

c.2025G>A

1 paper

NM_032656.4

p.E676D

c.2028G>T

2 papers

NM_032656.4

p.R671T

c.2012G>C

1 paper

NM_032656.4

p.E676D

c.2028G>C

1 paper

NM_032656.4

p.P677A

c.2029C>G

1 paper

NM_032656.4

p.G678S

c.2032G>A

1 paper

NM_032656.4

p.D666D

c.1998C>T

1 paper

NM_032656.4

p.A665S

c.1993G>T

1 paper

NM_032656.4

p.V649I

c.1945G>A

1 paper

NM_032656.4

p.G631D

c.1892G>A