Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032656.4

p.H442R

c.1325A>G

Surrounding Variants

1 paper

NM_032656.4

p.R446W

c.1336C>T

1 paper

NM_032656.4

p.R435S

c.1305G>T

1 paper

NM_032656.4

p.R458Q

c.1373G>A

11 papers

NM_032656.4

p.L467V

c.1399C>G

1 paper

NM_032656.4

p.P428L

c.1283C>T

6 papers

NM_032656.4

p.N419K

c.1257C>G

6 papers

NM_032656.4

p.N419K

c.1257C>A

4 papers

NM_032656.4

p.S408L

c.1223C>T

8 papers

NM_032656.4

p.T477M

c.1430C>T

4 papers

NM_032656.4

p.G478R

c.1432G>C

4 papers

NM_032656.4

p.G478R

c.1432G>A

2 papers

NM_032656.4

p.G478V

c.1433G>T