Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032656.4

p.S378R

c.1134C>G

Surrounding Variants

1 paper

NM_032656.4

p.S378R

c.1134C>A

1 paper

NM_032656.4

p.V379M

c.1135G>A

1 paper

NM_032656.4

p.S378R

c.1132A>C

4 papers

NM_032656.4

p.D382G

c.1145A>G

3 papers

NM_032656.4

p.G386S

c.1156G>A

1 paper

NM_032656.4

p.V369M

c.1105G>A

7 papers

NM_032656.4

p.R390H

c.1169G>A

1 paper

NM_032656.4

p.I391V

c.1171A>G

1 paper

NM_032656.4

p.L362P

c.1085T>C

1 paper

NM_032656.4

p.D360G

c.1079A>G

1 paper

NM_032656.4

p.D350V

c.1049A>T

1 paper

NM_032656.4

p.F347fs

c.1039_1040fs