Varaico: Literature-Extracted Genetic Variants

DHX37

147 papers

RefSeq Summary

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes ...

Pfam Domains

DEADaa 256–418UCSCDEAD/DEAH box helicase

Helicase_Caa 582–676UCSCHelicase conserved C-terminal domain

WHD_HA2aa 737–780UCSCHelicase associated domain (HA2), winged-helix

HA2_Caa 781–858UCSCHelicase associated domain (HA2), ratchet-like

OB_NTP_bindaa 925–1011UCSCOligonucleotide/oligosaccharide-binding (OB)-fold

DHX37_Caa 1076–1155UCSCDEAH helicase DHX37 C-terminal domain

Gene Aliases

HGNC Name

DEAH-box helicase 37

HGNC Previous Symbol

DDX37

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_032656.4

p.E186G

c.557A>G

Surrounding Variants

1 paper

NM_032656.4

p.E189G

c.566A>G

1 paper

NM_032656.4

p.E189D

c.567G>T

1 paper

NM_032656.4

p.E189D

c.567G>C

1 paper

NM_032656.4

p.E174_E178Fs

c.522_534delinsGGFs

2 papers

NM_032656.4

p.S177L

c.530C>T

1 paper

NM_032656.4

p.S177*

c.530C>A

1 paper

NM_032656.4

p.T195T

c.585C>T

1 paper

NM_032656.4

p.S169L

c.506C>T

7 papers

NM_032656.4

p.E168del1

c.502_503delCTC

1 paper

NM_032656.4

p.E167delins

c.500_501delinsTC

3 papers

NM_032656.4

p.E167A

c.500A>C

1 paper

NM_032656.4

p.R153L

c.458G>T