Varaico: Literature-Extracted Genetic Variants

DICER1

1,122 papers

RefSeq Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and i...

Pfam Domains

DEADaa 45–213UCSCDEAD/DEAH box helicase

Dicer_PBDaa 267–367UCSCDicer, partner-binding domain

Helicase_Caa 471–555UCSCHelicase conserved C-terminal domain

Dicer_dimeraa 630–719UCSCDicer dimerisation domain

Dicer_platformaa 761–887UCSCDicer, platform domain

PAZaa 894–1064UCSCPAZ domain

Gene Aliases

HGNC Name

dicer 1, ribonuclease III

HGNC Previous Symbol

MNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_177438.3

p.G1824V

c.5471G>T

Surrounding Variants

1 paper

NM_177438.3

p.G1824E

c.5471G>A

1 paper

NM_177438.3

p.G1824delins

c.5470_5471delinsAA

1 paper

NM_177438.3

p.G1824R

c.5470G>C

1 paper

NM_177438.3

p.G1824R

c.5470G>A

1 paper

NM_177438.3

p.S1823delFs

c.5469delA

3 papers

NM_177438.3

p.S1823fs

c.5467_5468fs

2 papers

NM_177438.3

p.S1823fs

c.5467_5468fs

1 paper

NM_177438.3

p.S1823_M1825Fs

c.5467_5475delinsGFs

1 paper

NM_177438.3

p.S1826P

c.5476T>C

6 papers

NM_177438.3

p.S1826*

c.5477C>G

6 papers

NM_177438.3

p.S1826*

c.5477C>A

12 papers

NM_177438.3

p.D1822V

c.5465A>T