Varaico: Literature-Extracted Genetic Variants

DICER1

1,122 papers

RefSeq Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and i...

Pfam Domains

DEADaa 45–213UCSCDEAD/DEAH box helicase

Dicer_PBDaa 267–367UCSCDicer, partner-binding domain

Helicase_Caa 471–555UCSCHelicase conserved C-terminal domain

Dicer_dimeraa 630–719UCSCDicer dimerisation domain

Dicer_platformaa 761–887UCSCDicer, platform domain

PAZaa 894–1064UCSCPAZ domain

Gene Aliases

HGNC Name

dicer 1, ribonuclease III

HGNC Previous Symbol

MNG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

131 papers

NM_177438.3

p.E1705K

c.5113G>A

Surrounding Variants

2 papers

NM_177438.3

p.E1705*

c.5113G>T

14 papers

NM_177438.3

p.E1705Q

c.5113G>C

17 papers

NM_177438.3

p.E1705V

c.5114A>T

1 paper

NM_177438.3

p.L1704F

c.5112A>T

6 papers

NM_177438.3

p.E1705A

c.5114A>C

1 paper

NM_177438.3

p.L1704F

c.5112A>C

2 papers

NM_177438.3

p.E1705D

c.5115A>T

2 papers

NM_177438.3

p.E1705D

c.5115A>C

1 paper

NM_177438.3

p.L1704V

c.5110T>G

3 papers

NM_177438.3

p.R1703C

c.5107C>T

1 paper

NM_177438.3

p.R1703S

c.5107C>A

1 paper

NM_177438.3

p.Q1702L

c.5105A>T