Varaico: Literature-Extracted Genetic Variants

DIS3L

61 papers

RefSeq Summary

The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a ca...

Pfam Domains

Rrp44_CSD1aa 224–323UCSCRrp44-like cold shock domain

OB_Dis3aa 364–432UCSCDis3-like cold-shock domain 2 (CSD2)

Gene Aliases

HGNC Name

DIS3 like exosome 3'-5' exoribonuclease

HGNC Alias Symbols

MGC4562; FLJ38088; KIAA1955; DIS3L1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001143688.3

p.D62N

c.184G>A

Surrounding Variants

1 paper

NM_001143688.3

p.V55M

c.163G>A

1 paper

NM_001143688.3

p.D54G

c.161A>G

1 paper

NM_001143688.3

p.R98I

c.293G>T