Varaico: Literature-Extracted Genetic Variants

Gene:DISC1
Variant:p.C187Y

DISC1

360 papers

RefSeq Summary

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through ...

Pfam Domains

DISC1_Caa 783–826UCSCDISC1 C-terminal domain

Gene Aliases

HGNC Name

DISC1 scaffold protein

HGNC Previous Name

disrupted in schizophrenia 1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_018662.3
p.C187Y
c.560G>A
Surrounding Variants
1 paper
NM_018662.3
p.G190R
c.568G>C
3 papers
NM_018662.3
p.P193S
c.577C>T
1 paper
NM_018662.3
p.A180G
c.539C>G
1 paper
NM_018662.3
p.P196A
c.586C>G
1 paper
NM_018662.3
p.L177Q
c.530T>A
1 paper
NM_018662.3
p.R170C
c.508C>T
1 paper
NM_018662.3
p.T207T
c.621C>G
3 papers
NM_018662.3
p.S209R
c.625A>C
3 papers
NM_018662.3
p.S209R
c.627C>A
3 papers
NM_018662.3
p.S209R
c.627C>G
1 paper
NM_018662.3
p.R214Q
c.641G>A
3 papers
NM_018662.3
p.W160L
c.479G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."