Varaico: Literature-Extracted Genetic Variants

Gene:DISC1
Variant:p.T754S

DISC1

360 papers

RefSeq Summary

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through ...

Pfam Domains

DISC1_Caa 783–826UCSCDISC1 C-terminal domain

Gene Aliases

HGNC Name

DISC1 scaffold protein

HGNC Previous Name

disrupted in schizophrenia 1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_018662.3
p.T754S
c.2260A>T
Surrounding Variants
6 papers
NM_018662.3
p.T754S
c.2261C>G
1 paper
NM_018662.3
p.E751A
c.2252A>C
7 papers
NM_018662.3
p.E751Q
c.2251G>C
3 papers
NM_018662.3
p.P758R
c.2273C>G
1 paper
NM_018662.3
p.V748I
c.2242G>A
2 papers
NM_018662.3
p.C762S
c.2284T>A
2 papers
NM_018662.3
p.C762S
c.2285G>C
1 paper
NM_018662.3
p.T744A
c.2230A>G
1 paper
NM_018662.3
p.K743R
c.2228A>G
1 paper
NM_018662.3
p.E739K
c.2215G>A
1 paper
NM_018662.3
p.L736L
c.2208C>T
1 paper
NM_018662.3
p.P734R
c.2201C>G
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