Varaico: Literature-Extracted Genetic Variants

DKK1

160 papers

RefSeq Summary

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The en...

Pfam Domains

Dickkopf_Naa 84–139UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 185–214UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 217–266UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 1

HGNC Alias Symbols

SK; DKK-1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 82 variants

17 papers

NM_012242.4

p.R120L

c.359G>T

4 papers

NM_012242.4

p.A41T

c.121G>A

4 papers

NM_012242.4

p.S157I

c.470G>T

3 papers

NM_012242.4

p.N72Y

c.214A>T

3 papers

NM_012242.4

p.Y74F

c.221A>T

3 papers

NM_012242.4

p.G183Splc

c.548-4G>T

3 papers

NM_012242.4

p.G183Splc

c.548-3T>C

2 papers

NM_012242.4

p.L33W

c.98T>G

2 papers

NM_012242.4

p.G65V

c.194G>T

2 papers

NM_012242.4

p.G71R

c.211G>A

2 papers

NM_012242.4

p.G71R

c.211G>C

2 papers

NM_012242.4

p.Q81L

c.242A>T