Varaico: Literature-Extracted Genetic Variants

DKK1

160 papers

RefSeq Summary

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The en...

Pfam Domains

Dickkopf_Naa 84–139UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 185–214UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 217–266UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 1

HGNC Alias Symbols

SK; DKK-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_012242.4

p.L33W

c.98T>G

Surrounding Variants

1 paper

NM_012242.4

p.S39Y

c.116C>A

4 papers

NM_012242.4

p.A41T

c.121G>A

1 paper

NM_012242.4

p.P25S

c.73C>T

1 paper

NM_012242.4

p.G22D

c.65G>A

1 paper

NM_012242.4

p.A20del1

c.58_59delGCT

1 paper

NM_012242.4

p.A19V

c.56C>T

1 paper

NM_012242.4

p.A19_A20del1

c.57_59delGGC

1 paper

NM_012242.4

p.M16L

c.46A>C

1 paper

NM_012242.4

p.M16L

c.46A>T

1 paper

NM_012242.4

p.V14D

c.41T>A

1 paper

NM_012242.4

p.A53A

c.159G>A

1 paper

NM_012242.4

p.G57_A59del3

c.169_176del9