Varaico: Literature-Extracted Genetic Variants

DKK1

160 papers

RefSeq Summary

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The en...

Pfam Domains

Dickkopf_Naa 84–139UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 185–214UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 217–266UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 1

HGNC Alias Symbols

SK; DKK-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_012242.4

p.G71R

c.211G>C

Surrounding Variants

2 papers

NM_012242.4

p.G71R

c.211G>A

1 paper

NM_012242.4

p.G70D

c.209G>A

3 papers

NM_012242.4

p.N72Y

c.214A>T

1 paper

NM_012242.4

p.G70S

c.208G>A

3 papers

NM_012242.4

p.Y74F

c.221A>T

2 papers

NM_012242.4

p.G65V

c.194G>T

2 papers

NM_012242.4

p.Q81L

c.242A>T

1 paper

NM_012242.4

p.S58F

c.173C>T

1 paper

NM_012242.4

p.G57_A59del3

c.169_176del9

1 paper

NM_012242.4

p.A53A

c.159G>A

4 papers

NM_012242.4

p.A41T

c.121G>A

1 paper

NM_012242.4

p.S39Y

c.116C>A