Varaico: Literature-Extracted Genetic Variants

DKK1

160 papers

RefSeq Summary

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The en...

Pfam Domains

Dickkopf_Naa 84–139UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 185–214UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 217–266UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 1

HGNC Alias Symbols

SK; DKK-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012242.4

p.E89G

c.266A>G

Surrounding Variants

1 paper

NM_012242.4

p.E90*

c.268G>T

1 paper

NM_012242.4

p.A86T

c.256G>A

1 paper

NM_012242.4

p.D94G

c.281A>G

2 papers

NM_012242.4

p.P84L

c.251C>T

1 paper

NM_012242.4

p.A98P

c.292G>C

1 paper

NM_012242.4

p.G103E

c.308G>A

1 paper

NM_012242.4

p.Q81_P82Splc

c.244-23C>T

1 paper

NM_012242.4

p.A106T

c.316G>A

2 papers

NM_012242.4

p.A106A

c.318A>G

1 paper

NM_012242.4

p.L112R

c.335T>G

1 paper

NM_012242.4

p.R115G

c.343A>G

1 paper

NM_012242.4

p.K116delFs

c.346delA