Varaico: Literature-Extracted Genetic Variants

DKK1

160 papers

RefSeq Summary

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The en...

Pfam Domains

Dickkopf_Naa 84–139UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 185–214UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 217–266UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 1

HGNC Alias Symbols

SK; DKK-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_012242.4

p.S157I

c.470G>T

Surrounding Variants

1 paper

NM_012242.4

p.G159A

c.476G>C

1 paper

NM_012242.4

p.D161N

c.481G>A

1 paper

NM_012242.4

p.E151Q

c.451G>C

1 paper

NM_012242.4

p.G167E

c.500G>A

1 paper

NM_012242.4

p.Y168F

c.503A>T

1 paper

NM_012242.4

p.D142Y

c.424G>T

1 paper

NM_012242.4

p.Y179F

c.536A>T

2 papers

NM_012242.4

p.G183Splc

c.548-43A>G

3 papers

NM_012242.4

p.G183Splc

c.548-4G>T

3 papers

NM_012242.4

p.G183Splc

c.548-3T>C

1 paper

NM_012242.4

p.R191Q

c.572G>A

1 paper

NM_012242.4

p.R203delFs

c.607_608delAG