Varaico: Literature-Extracted Genetic Variants

DKK2

76 papers

RefSeq Summary

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the ...

Pfam Domains

Dickkopf_Naa 77–128UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 179–208UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 211–259UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 2

HGNC Previous Names

dickkopf WNT signaling pathway inhibitor 2; dickkopf (Xenopus laevis) homolog 2; dickkopf 2 homolog (Xenopus laevis)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 58 variants

10 papers

NM_014421.3

p.R146Q

c.437G>A

3 papers

NM_014421.3

p.G96R

c.286G>C

3 papers

NM_014421.3

p.G96R

c.286G>A

2 papers

NM_014421.3

p.H138Y

c.412C>T

2 papers

NM_014421.3

p.E226K

c.676G>A

2 papers

NM_014421.3

p.R230H

c.689G>A

1 paper

NM_014421.3

p.A3V

c.8C>T

1 paper

NM_014421.3

p.L4F

c.12G>C

1 paper

NM_014421.3

p.L4L

c.12G>A

1 paper

NM_014421.3

p.D9Y

c.25G>T

1 paper

NM_014421.3

p.S10L

c.29C>T

1 paper

NM_014421.3

p.S10*

c.29C>A