Varaico: Literature-Extracted Genetic Variants

DKK2

76 papers

RefSeq Summary

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the ...

Pfam Domains

Dickkopf_Naa 77–128UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 179–208UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 211–259UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 2

HGNC Previous Names

dickkopf WNT signaling pathway inhibitor 2; dickkopf (Xenopus laevis) homolog 2; dickkopf 2 homolog (Xenopus laevis)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014421.3

p.G177W

c.529G>T

Surrounding Variants

1 paper

NM_014421.3

p.L184P

c.551T>C

1 paper

NM_014421.3

p.R185Q

c.554G>A

1 paper

NM_014421.3

p.I190N

c.569T>A

1 paper

NM_014421.3

p.R197H

c.590G>A

1 paper

NM_014421.3

p.E212D

c.636A>T

1 paper

NM_014421.3

p.E212D

c.636A>C

1 paper

NM_014421.3

p.V213F

c.637G>T

1 paper

NM_014421.3

p.S222Y

c.665C>A

2 papers

NM_014421.3

p.E226K

c.676G>A

1 paper

NM_014421.3

p.R230C

c.688C>T

2 papers

NM_014421.3

p.R230H

c.689G>A

1 paper

NM_014421.3

p.K235N

c.705G>T