Varaico: Literature-Extracted Genetic Variants

DKK2

76 papers

RefSeq Summary

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the ...

Pfam Domains

Dickkopf_Naa 77–128UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 179–208UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 211–259UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 2

HGNC Previous Names

dickkopf WNT signaling pathway inhibitor 2; dickkopf (Xenopus laevis) homolog 2; dickkopf 2 homolog (Xenopus laevis)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014421.3

p.T131T

c.393T>A

Surrounding Variants

2 papers

NM_014421.3

p.H138Y

c.412C>T

1 paper

NM_014421.3

p.G144G

c.432T>C

10 papers

NM_014421.3

p.R146Q

c.437G>A

1 paper

NM_014421.3

p.R150L

c.449G>T

1 paper

NM_014421.3

p.G153S

c.457G>A

1 paper

NM_014421.3

p.W162*

c.485G>A

1 paper

NM_014421.3

p.W162*

c.486G>A

1 paper

NM_014421.3

p.H169R

c.506A>G

1 paper

NM_014421.3

p.I175K

c.524T>A

1 paper

NM_014421.3

p.K176E

c.526A>G

1 paper

NM_014421.3

p.G177W

c.529G>T

1 paper

NM_014421.3

p.G177W

c.529G>T