Varaico: Literature-Extracted Genetic Variants

DKK2

76 papers

RefSeq Summary

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the ...

Pfam Domains

Dickkopf_Naa 77–128UCSCDickkopf N-terminal cysteine-rich region

DIKK1-2-4_C-subdom1aa 179–208UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 1

DIKK1-2-4_C-subdom2aa 211–259UCSCDickkopf-related protein 1/2/4, C-terminal subdomain 2

Gene Aliases

HGNC Name

dickkopf Wnt signaling pathway inhibitor 2

HGNC Previous Names

dickkopf WNT signaling pathway inhibitor 2; dickkopf (Xenopus laevis) homolog 2; dickkopf 2 homolog (Xenopus laevis)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014421.3

p.G96R

c.286G>A

Surrounding Variants

3 papers

NM_014421.3

p.G96R

c.286G>C

1 paper

NM_014421.3

p.S97L

c.290C>T

1 paper

NM_014421.3

p.P93T

c.277C>A

1 paper

NM_014421.3

p.H91N

c.271C>A

1 paper

NM_014421.3

p.M101I

c.303G>T

1 paper

NM_014421.3

p.M101I

c.303G>C

1 paper

NM_014421.3

p.M101I

c.303G>A

1 paper

NM_014421.3

p.C90Y

c.269G>A

1 paper

NM_014421.3

p.G87W

c.259G>T

1 paper

NM_014421.3

p.C110Y

c.329G>A

1 paper

NM_014421.3

p.D81V

c.242A>T

1 paper

NM_014421.3

p.D81N

c.241G>A