Varaico: Literature-Extracted Genetic Variants

Gene:DMC1
Variant:p.P287H

DMC1

142 papers

RefSeq Summary

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. ...

Pfam Domains

HHH_5aa 23–79UCSCHelix-hairpin-helix domain
Rad51aa 94–338UCSCRad51

Gene Aliases

HGNC Name

DNA meiotic recombinase 1

HGNC Alias Symbol

LIM15

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_007068.4
p.P287H
c.860C>A
Surrounding Variants
1 paper
NM_007068.4
p.P287S
c.859C>T
1 paper
NM_007068.4
p.K286insFs
c.858dupA
1 paper
NM_007068.4
p.P287fs
c.859_860fs
4 papers
NM_007068.4
p.I288T
c.863T>C
1 paper
NM_007068.4
p.K285R
c.854A>G
1 paper
NM_007068.4
p.G290del1
c.868_870delTCC
1 paper
NM_007068.4
p.G289_G290del2
c.865_869del6
1 paper
NM_007068.4
p.H295Y
c.883C>T
1 paper
NM_007068.4
p.S297delFs
c.890delG
1 paper
NM_007068.4
p.R304*
c.910C>T
1 paper
NM_007068.4
p.K305fs
c.913_914fs
1 paper
NM_007068.4
p.R307K
c.920G>A
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