Varaico: Literature-Extracted Genetic Variants

Gene:DMC1
Variant:p.Q243E

DMC1

142 papers

RefSeq Summary

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. ...

Pfam Domains

HHH_5aa 23–79UCSCHelix-hairpin-helix domain
Rad51aa 94–338UCSCRad51

Gene Aliases

HGNC Name

DNA meiotic recombinase 1

HGNC Alias Symbol

LIM15

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_007068.4
p.Q243E
c.727C>G
Surrounding Variants
2 papers
NM_007068.4
p.K245E
c.733A>G
1 paper
NM_007068.4
p.M249V
c.745A>G
1 paper
NM_007068.4
p.R252G
c.754C>G
1 paper
NM_007068.4
p.D232_F233insTT
c.694_698ins6
1 paper
NM_007068.4
p.R230delFs
c.689_690delTC
2 papers
NM_007068.4
p.M226_A227delFs
c.678_681del4
1 paper
NM_007068.4
p.E258G
c.773A>G
2 papers
NM_007068.4
p.E258A
c.773A>C
1 paper
NM_007068.4
p.D223N
c.667G>A
1 paper
NM_007068.4
p.I221T
c.662T>C
1 paper
NM_007068.4
p.F217_K218delFs
c.651_652delTG
1 paper
NM_007068.4
p.F217Y
c.650T>A
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