Varaico: Literature-Extracted Genetic Variants

Gene:DMC1
Variant:p.T122A

DMC1

142 papers

RefSeq Summary

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. ...

Pfam Domains

HHH_5aa 23–79UCSCHelix-hairpin-helix domain
Rad51aa 94–338UCSCRad51

Gene Aliases

HGNC Name

DNA meiotic recombinase 1

HGNC Alias Symbol

LIM15

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_007068.4
p.T122A
c.364A>G
Surrounding Variants
1 paper
NM_007068.4
p.I121_T122ins1
c.363_364insACA
1 paper
NM_007068.4
p.T122I
c.365C>T
1 paper
NM_007068.4
p.D109Splc
c.327-1538T>C
2 papers
NM_007068.4
p.R129C
c.385C>T
1 paper
NM_007068.4
p.R129L
c.386G>T
2 papers
NM_007068.4
p.K132R
c.395A>G
1 paper
NM_007068.4
p.L135_S136del2
c.403_407del6
1 paper
NM_007068.4
p.V141Splc
c.421+1G>A
1 paper
NM_007068.4
p.G150D
c.449G>A
1 paper
NM_007068.4
p.G153R
c.457G>C
1 paper
NM_007068.4
p.G153R
c.457G>A
1 paper
NM_007068.4
p.G153E
c.458G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."