DnaJ heat shock protein family (Hsp40) member C24

ZCSL3

DPH4

JJJ3

zinc finger, CSL-type containing 3

DPH4 homolog (JJJ3, S. cerevisiae)

DPH4, JJJ3 homolog (S. cerevisiae)

DnaJ (Hsp40) homolog, subfamily C, member 24

DnaJ homolog subfamily C member 24

CSL-type zinc finger-containing protein 3

Diphthamide biosynthesis protein 4

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008].

Varaico: Literature-Extracted Genetic Variants

DNAJC24

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbols