Varaico: Literature-Extracted Genetic Variants

DNMT3L

80 papers

RefSeq Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required...

Pfam Domains

ADD_DNMT3aa 34–89UCSCDNMT3, cysteine rich ADD domain, GATA1-like zinc finger

DNMT3_ADD_GATA1-likeaa 96–145UCSCDNMT3, ADD PHD zinc finger

Gene Aliases

HGNC Name

DNA methyltransferase 3 like

HGNC Alias Symbol

MGC1090

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_175867.3

p.P310S

c.928C>T

Surrounding Variants

1 paper

NM_175867.3

p.S325N

c.974G>A

1 paper

NM_175867.3

p.N326S

c.977A>G

1 paper

NM_175867.3

p.P328T

c.982C>A

1 paper

NM_175867.3

p.R331K

c.992G>A

1 paper

NM_175867.3

p.E303_M304Splc

c.909+10G>T

8 papers

NM_175867.3

p.R278G

c.832A>G

1 paper

NM_175867.3

p.G275R

c.823G>C

5 papers

NM_175867.3

p.R271Q

c.812G>A

1 paper

NM_175867.3

p.A270T

c.808G>A

1 paper

NM_175867.3

p.H264H

c.792C>T

1 paper

NM_175867.3

p.V241M

c.721G>A

1 paper

NM_175867.3

p.F238F

c.714C>T