Varaico: Literature-Extracted Genetic Variants

DNMT3L

80 papers

RefSeq Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required...

Pfam Domains

ADD_DNMT3aa 34–89UCSCDNMT3, cysteine rich ADD domain, GATA1-like zinc finger

DNMT3_ADD_GATA1-likeaa 96–145UCSCDNMT3, ADD PHD zinc finger

Gene Aliases

HGNC Name

DNA methyltransferase 3 like

HGNC Alias Symbol

MGC1090

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_175867.3

p.C73C

c.219C>T

Surrounding Variants

1 paper

NM_175867.3

p.G70E

c.209G>A

1 paper

NM_175867.3

p.H62Y

c.184C>T

1 paper

NM_175867.3

p.V61G

c.182T>G

1 paper

NM_175867.3

p.C53Y

c.158G>A

1 paper

NM_175867.3

p.L84F

c.250C>T

1 paper

NM_175867.3

p.S94T

c.280T>A

1 paper

NM_175867.3

p.Y95H

c.283T>C

1 paper

NM_175867.3

p.S101S

c.303C>T

1 paper

NM_175867.3

p.G102*

c.304G>T

1 paper

NM_175867.3

p.G109G

c.327A>G

1 paper

NM_175867.3

p.C113F

c.338G>T

1 paper

NM_175867.3

p.G127C

c.379G>T