Varaico: Literature-Extracted Genetic Variants

DNTT

114 papers

RefSeq Summary

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleoti...

Pfam Domains

BRCTaa 27–111UCSCBRCA1 C Terminus (BRCT) domain

HHH_8aa 163–234UCSCHelix-hairpin-helix domain

DNA_pol_lambd_faa 250–300UCSCFingers domain of DNA polymerase lambda

NTP_transf_2aa 311–403UCSCNucleotidyltransferase domain

DNA_pol_B_thumbaa 445–508UCSCDNA polymerase beta thumb

Gene Aliases

HGNC Name

DNA nucleotidylexotransferase

HGNC Alias Symbols

TDT; TdT

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004088.4

p.D34D

c.102T>C

Surrounding Variants

1 paper

NM_004088.4

p.Q33R

c.98A>G

5 papers

NM_004088.4

p.V37I

c.109G>A

1 paper

NM_004088.4

p.M23T

c.68T>C

1 paper

NM_004088.4

p.T47T

c.141C>T

1 paper

NM_004088.4

p.A21V

c.62C>T

1 paper

NM_004088.4

p.R48C

c.142C>T

1 paper

NM_004088.4

p.R17Q

c.50G>A

1 paper

NM_004088.4

p.R17W

c.49C>T

1 paper

NM_004088.4

p.L52L

c.156C>A

1 paper

NM_004088.4

p.R15K

c.44G>A

1 paper

NM_004088.4

p.E54D

c.162G>C

1 paper

NM_004088.4

p.E54D

c.162G>T