Varaico: Literature-Extracted Genetic Variants

DOCK5

142 papers

RefSeq Summary

This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by thi...

Pfam Domains

SH3_1aa 14–55UCSCSH3 domain

DOCK_Naa 71–434UCSCDOCK N-terminus

DOCK-C2aa 439–636UCSCC2 domain in Dock180 and Zizimin proteins

TPR_DOCKaa 646–1175UCSCDedicator of cytokinesis (DOCK) TPR region

DHR-2_Lobe_Aaa 1223–1354UCSCDHR-2, Lobe A

DHR-2_Lobe_Baa 1411–1494UCSCDHR-2, Lobe B

Gene Aliases

HGNC Name

dedicator of cytokinesis 5

HGNC Alias Symbol

FLJ21034

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024940.8

p.V736A

c.2207T>C

Surrounding Variants

1 paper

NM_024940.8

p.N743Y

c.2227A>T

1 paper

NM_024940.8

p.S747P

c.2239T>C

1 paper

NM_024940.8

p.R765S

c.2295A>C

1 paper

NM_024940.8

p.R765S

c.2295A>T

1 paper

NM_024940.8

p.Q710Q

c.2130G>A

1 paper

NM_024940.8

p.V698G

c.2093T>G

1 paper

NM_024940.8

p.M683V

c.2047A>G

1 paper

NM_024940.8

p.Q670_D671insT

c.2008_2012ins3

1 paper

NM_024940.8

p.L654I

c.1960C>A

1 paper

NM_024940.8

p.K651I

c.1952A>T

1 paper

NM_024940.8

p.G639R

c.1915G>C

1 paper

NM_024940.8

p.M800R

c.2399T>G