Varaico: Literature-Extracted Genetic Variants

DOCK5

142 papers

RefSeq Summary

This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by thi...

Pfam Domains

SH3_1aa 14–55UCSCSH3 domain

DOCK_Naa 71–434UCSCDOCK N-terminus

DOCK-C2aa 439–636UCSCC2 domain in Dock180 and Zizimin proteins

TPR_DOCKaa 646–1175UCSCDedicator of cytokinesis (DOCK) TPR region

DHR-2_Lobe_Aaa 1223–1354UCSCDHR-2, Lobe A

DHR-2_Lobe_Baa 1411–1494UCSCDHR-2, Lobe B

Gene Aliases

HGNC Name

dedicator of cytokinesis 5

HGNC Alias Symbol

FLJ21034

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024940.8

p.V810F

c.2428G>T

Surrounding Variants

2 papers

NM_024940.8

p.M800I

c.2400G>A

2 papers

NM_024940.8

p.M800I

c.2400G>C

2 papers

NM_024940.8

p.M800I

c.2400G>T

1 paper

NM_024940.8

p.M800R

c.2399T>G

1 paper

NM_024940.8

p.I824S

c.2471T>G

1 paper

NM_024940.8

p.S846C

c.2536A>T

1 paper

NM_024940.8

p.L868V

c.2602C>G

2 papers

NM_024940.8

p.R870*

c.2608C>T

1 paper

NM_024940.8

p.T883R

c.2648C>G

1 paper

NM_024940.8

p.L886L

c.2658C>T

1 paper

NM_024940.8

p.E900K

c.2698G>A

1 paper

NM_024940.8

p.S903S

c.2709G>A