Varaico: Literature-Extracted Genetic Variants

DOCK5

142 papers

RefSeq Summary

This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by thi...

Pfam Domains

SH3_1aa 14–55UCSCSH3 domain

DOCK_Naa 71–434UCSCDOCK N-terminus

DOCK-C2aa 439–636UCSCC2 domain in Dock180 and Zizimin proteins

TPR_DOCKaa 646–1175UCSCDedicator of cytokinesis (DOCK) TPR region

DHR-2_Lobe_Aaa 1223–1354UCSCDHR-2, Lobe A

DHR-2_Lobe_Baa 1411–1494UCSCDHR-2, Lobe B

Gene Aliases

HGNC Name

dedicator of cytokinesis 5

HGNC Alias Symbol

FLJ21034

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024940.8

p.M987L

c.2959A>C

Surrounding Variants

2 papers

NM_024940.8

p.M987L

c.2959A>T

1 paper

NM_024940.8

p.I983_D984Splc

c.2950-4G>A

1 paper

NM_024940.8

p.L996L

c.2988G>A

1 paper

NM_024940.8

p.D1005G

c.3014A>G

4 papers

NM_024940.8

p.Q1023R

c.3068A>G

1 paper

NM_024940.8

p.N1044K

c.3132C>A

1 paper

NM_024940.8

p.N1044K

c.3132C>G

2 papers

NM_024940.8

p.A1050A

c.3150A>G

3 papers

NM_024940.8

p.E1057G

c.3170A>G

1 paper

NM_024940.8

p.R1069H

c.3206G>A

1 paper

NM_024940.8

p.S974R

c.2920A>C

1 paper

NM_024940.8

p.C956F

c.2867G>T