Varaico: Literature-Extracted Genetic Variants

DOCK5

142 papers

RefSeq Summary

This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by thi...

Pfam Domains

SH3_1aa 14–55UCSCSH3 domain

DOCK_Naa 71–434UCSCDOCK N-terminus

DOCK-C2aa 439–636UCSCC2 domain in Dock180 and Zizimin proteins

TPR_DOCKaa 646–1175UCSCDedicator of cytokinesis (DOCK) TPR region

DHR-2_Lobe_Aaa 1223–1354UCSCDHR-2, Lobe A

DHR-2_Lobe_Baa 1411–1494UCSCDHR-2, Lobe B

Gene Aliases

HGNC Name

dedicator of cytokinesis 5

HGNC Alias Symbol

FLJ21034

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024940.8

p.P1439R

c.4316C>G

Surrounding Variants

1 paper

NM_024940.8

p.R1391Q

c.4172G>A

1 paper

NM_024940.8

p.R1391*

c.4171C>T

1 paper

NM_024940.8

p.P1467L

c.4400C>T

1 paper

NM_024940.8

p.E1472Q

c.4414G>C

1 paper

NM_024940.8

p.R1486Q

c.4457G>A

1 paper

NM_024940.8

p.T1490M

c.4469C>T

1 paper

NM_024940.8

p.A1518S

c.4552G>T

1 paper

NM_024940.8

p.E1520K

c.4558G>A

1 paper

NM_024940.8

p.N1526N

c.4578C>T

1 paper

NM_024940.8

p.W1538R

c.4612T>A

1 paper

NM_024940.8

p.W1538R

c.4612T>C

1 paper

NM_024940.8

p.P1557L

c.4670C>T