Varaico: Literature-Extracted Genetic Variants

Gene:DRD4
Variant:p.V139M

DRD4

361 papers

RefSeq Summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkin...

Pfam Domains

7tm_1aa 51–400UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

dopamine receptor D4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000797.4
p.V139M
c.415G>A
Surrounding Variants
1 paper
NM_000797.4
p.P140L
c.419C>T
1 paper
NM_000797.4
p.V137M
c.409G>A
3 papers
NM_000797.4
p.A136A
c.408C>G
1 paper
NM_000797.4
p.L141P
c.422T>C
1 paper
NM_000797.4
p.L141L
c.423G>A
1 paper
NM_000797.4
p.R142R
c.426C>T
1 paper
NM_000797.4
p.Y143C
c.428A>G
1 paper
NM_000797.4
p.A138_V139ins0
c.412_417dup6
1 paper
NM_000797.4
p.R145Q
c.434G>A
1 paper
NM_000797.4
p.R145_Q146insFs
c.435_436insTG
1 paper
NM_000797.4
p.G148G
c.444G>A
2 papers
NM_000797.4
p.R151Q
c.452G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."