Varaico: Literature-Extracted Genetic Variants

Gene:DRD4
Variant:p.A225V

DRD4

361 papers

RefSeq Summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkin...

Pfam Domains

7tm_1aa 51–400UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

dopamine receptor D4

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000797.4
p.A225V
c.674C>T
Surrounding Variants
1 paper
NM_000797.4
p.A225S
c.673G>T
1 paper
NM_000797.4
p.R227H
c.680G>A
1 paper
NM_000797.4
p.R227L
c.680G>T
1 paper
NM_000797.4
p.K229R
c.686A>G
1 paper
NM_000797.4
p.R221H
c.662G>A
2 papers
NM_000797.4
p.R233_S245del13
c.697_734del39
2 papers
NM_000797.4
p.P235_T247del13
c.703_740del39
1 paper
NM_000797.4
p.R237Q
c.710G>A
2 papers
NM_000797.4
p.R237L
c.710G>T
1 paper
NM_000797.4
p.Y212C
c.635A>G
1 paper
NM_000797.4
p.P238R
c.713C>G
1 paper
NM_000797.4
p.P238L
c.713C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."